Obesity and depression: its prevalence and influence as a prognostic factor: a systematic review
Eli Lilly, the manufacturer of brand-name tirzepatide (Mounjaro and Zepbound), has pushed back against compounded versions of their drug, arguing that compounding pharmacies should not be producing copies of medications that are commercially available
For anyone who wants to lose weight naturally and sustainably, there are effective alternatives: diet, exercise, mindfulness and healthy gut flora are key levers for balancing the metabolism and thus strengthening the body and well-being.
Early phase 2 data for retatrutide, published in the New England Journal of Medicine in 2023, showed weight loss of up to about 24% over 48 weeks, with additional improvements in fasting glucose and insulin sensitivity
JAMA Internal Medicine analyzed 18,386 matched pairs in a retrospective EHR cohort and found tirzepatide at 15.3% and semaglutide at 8.3% weight loss at 12 months