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Another remarkable feature of cells undergoing apoptosis is that they rapidly and selectively release a large fraction of their intracellular GSH into the extracellular space (van den Dobbelsteen et al., 1996

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The weight loss plateau that appears 1216 weeks into treatment and stabilizes before the trial endpoint is consistent with progressive attenuation of the appetite-suppressing signal whether through receptor desensitization in the lateral septum, hypothalamus, or dorsal vagal complex

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