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As a key part of the bodys endogenous defense mechanism, the presence of glutathione neutralizes and reduces these free radicals.* The production of ROS increases with age, at the same time our internal defense mechanisms weaken, resulting in oxidative stress an imbalance where ROS outnumber antioxidants in the body

One important feature of mitochondrial permeabilization is the loss of function resulting in the inability of mitochondria to synthesize ATP through the OXPHOS

Excessive metabolization of ATP to ADP may determine the course of inflammation

Pharmacological potential of ginseng and its major component ginsenosides

El-Sehrawy et al., 2025)