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In obese subjects, overpopulated immune cells (mainly macrophages) and dysfunctional adipocytes secrete a variety of cytokines and chemokines, causing low-grade long-term inflammation in AT, which plays a determining role in metabolic diseases, such as cardiovascular diseases, liver steatosis and type 2 diabetes [2]
(10) Considering the potential lipolytic action of Fragment 176-191 and CJC-1295, researchers may want to consider the hypothesis that the blend of these peptides may counteract the fat-increasing potential of Ipamorelin, while further increasing its muscle building potential
doi: 10.1371/journal.pone.0087716 10 TseliosKKoumarasCUrowitzMBGladmanDD
