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CONTRAINDICATIONS: Sensitivity to cobalt and/or vitamin B12 is a contraindication

But its one of those things that you probably dont think about needing until you have symptoms of not having enough of it

Salinas et al 27 The traditional treatment of vitamin B 12 deficiency is the intramuscular injection of cyanocobalamin, generally, 1 mg/d for 1 week, followed by 1 mg/wk for 1 month, and then 1 mg every 1 or2 months ad perpetuum

Homocysteine and preeclampsia Higher levels of homocysteine have been associated with hypertension, heart disease, stroke, high blood pressure, and preeclampsia, among several other conditions

doi:10.1007/s00277-013-1901-3 [38] Brighten J