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All cited studies are conducted in rodent or in-vitro systems
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In addition, there was a significant nonlinear relationship between dose (2 g/day) and changes in insulin, as well as a significant linear relationship between the duration (weeks) (coefficients = 16.45, p = 0.004) of intervention and changes in HbA1C
The compound is derived from an endogenous neuropeptide that exists naturally in human cerebrospinal fluid, which may explain its favorable tolerability
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In this review, we aimed to understand the role of adipogenesis in obesity-associated IR and T2DM by screening 2317 articles investigating adipogenesis and mediators of impaired adipogenesis in PubMed with the aid of Rayyne, a systematic review web application [36]
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