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This protective effect is attributed to the ability of Lactobacillus casei Shirota (LcS) to stimulate the secretion of TNF- and interleukin-12 (IL-12), cytokines that are well-established drivers of enhanced NK cell cytotoxic activity (194)

Setria Glutathione is made to be highly bioavailable, more so than standard glutathione

Diabetic enteropathies including small bowel dysmotility syndromes, diabetic diarrhea and fecal incontinence [20] Gut complications of diabetes, including diabetic diarrhea and incontinence, small intestinal bacterial overgrowth, non-alcoholic fatty liver disease and exocrine pancreatitis, have a major impact on health outcomes in individuals with long- standing poorly controlled diabetes

Table 10: Analyses of the Primary and Secondary Endpoints and their Individual Components in FLOW Trial 1 Cox proportional hazards model with treatment as factor and stratified by baseline use of SGLT2-inhibitor at baseline (yes or no)

More targets equals more efficacy