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However, the number of cases was very minimal, and cases occurred equally in both the GLP-1 RA and placebo groups

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While we have not ruled out the possibility that ML162 may delay Wallerian degeneration, our results support that the combined treatment of ML162 and PEG prevents axon degeneration and NMJ denervation, possibly by promoting axonal fusion (Fig

This is also consistent with the emerging role of NRF2 in promoting stem cell properties in cancer cells [57]

One of the most significant side effects of current GLP-1 receptor agonists like semaglutide is nausea possibly linked to how and where these drugs act in the brain