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The reduction in GSSG levels might represent a distinct pathophysiological state in acute relapse, possibly involving different mechanisms from those in first-episode or stable phases of the illness [32]

Thus, OS in DM represents a paradigm of metabolic memory, where initial oxidative damage perpetuates dysfunction long after glycemic control is achieved, underscoring the need for early redox-targeted therapies

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Successfully adding any new active ingredient is all about understanding where it fits, what concentration to aim for, and which other ingredients will be its best friends