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Patients with childbearing potential who are not interested in conceiving should be counseled about using appropriate contraceptive methods while taking GLP-1 medications, and the medication should be stopped immediately if a patient becomes pregnant

Perspective, Challenges, and Future Directions Despite the promising roles of glutamine deprivation strategies and supplementation in cancer therapy, several challenges persist, including the need for a comprehensive understanding of the metabolic adaptation of cancer cells, personalized delivery methods, and identifying patient subgroups likely to benefit the most (Figure 3 and Figure 4)