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Intravenous (IV) Glutathione IV glutathione is administered through an injection directly into the bloodstream, ensuring maximum absorption and immediate effects

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However, under conditions of oxidative stress, superoxide radicals (O2) react with NO to form ONOO , reducing the bioavailability of NO and leading to endothelial dysfunction [67]

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Our identification of VRK2-mediated SLC7A11 trafficking suggests a potential immune evasion mechanism, as SLC7A11-high tumors often display T cell exclusion phenotypes [37], warranting future investigation into whether VRK2 expression could predict therapeutic response to combined ferroptosis inducers and immune checkpoint inhibitors