Dissolved under the tongue, which allows some absorption through the oral mucosa and bypasses the stomach and intrinsic factor pathway
Considering the number of patients and the few reported cases, you can see how rare these reactions really are
This can be especially important for individuals with MTHFR gene mutation, as it may help support methylation processes and overall health
[DOI] [PMC free article] [PubMed] [Google Scholar] 58.Waibel R., Treichler H., Schaefer N.G., van Staveren D.R., Mundwiler S., Kunze S., Kuenzi M., Alberto R., Nuesch J., Knuth A., et al
In fact, Madonna, Rita Ora, Charlize Theron, Katy Perry, and Justin Timberlake swear by its effectiveness, saying that this powerful nutrient help them reduce weight while increasing their energy levels