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Drugs associated with neurexins modulating synaptic plasticity To understanding the potential of neurexin-modulated synaptic plasticity in sustained antidepressant effect, we further summarize the drugs that may be involved in the modulation of synaptic plasticity by neurexins to expand the drug pool and link depression in depth to unlock the potential that these drugs may have in antidepressant or sustained antidepressant effect

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adding another GLP-1 compound creates redundancy and additional side-effect burden without a new pathway benefit