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Historical Background and Scientific Context Scientific interest in DSIP emerged during the twentieth century as researchers expanded their understanding of naturally occurring peptide signalling molecules and their role within complex biological systems

In addition, end-stage renal disease (ESRD) has been a misery dilemma faced by more than 2 million patients with the exacerbation of renal function worldwide [4] and the number is still keeping a rapidly rising trend, resulting in a heavy burden on public health and medical care [5, 6]

FIGURE 3 8.7 The role of ferroptosis in atherosclerosis with depression Ferroptosis influences the onset of AS and depression through inflammation, mitochondrial dysfunction, and gut microbiota, respectively

Push and turn the needle onto the pen until tight