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Pejman Katiraei: We think of it as the cartoon character, but it turns out that Sonic Hedgehog actually orchestrates this entire complex cascade of immune behavior

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Inhibition of glutathione metabolism by BSO decreased the ESCC tumor burden To investigate whether glutathione metabolism contributed to the progression of ESCC development, we treated mice bearing ESCC 20 weeks after initial carcinogen treatment with buthionine sulfoximine (BSO), a commonly used chemical inhibitor of -glutamylcysteine synthetase (-GCS) that decreases tissue glutathione concentrations (Figure 3a)

Functional characterization of the ferroxidase, permease high-affinity iron transport complex from Candida albicans

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