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The combination is thus a prime example of the strategy of combining two complementary satiety signals rather than simply stimulating a single receptor pathway more strongly

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One RAR will partner with a retinoid X receptor (RXR) and make a heterodimer.[17] RAR-gamma accounts for about 90 percent of RARs in the epidermis, and RXR-alpha accounts for roughly 90 percent of the RXRs

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