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This review does not provide an exhaustive, comprehensive review of the literature

The STEP trials (published 2021-2022) enrolled over 4,500 participants

Therefore, the key to the individualized treatment of ecological therapy in future is to explore the premise of effective probiotics implantation and understand the degree of inter-individual variation of the sensitivity of microbiota to probiotics intervention

Because B12 is primarily found in animal products (meat, fish, dairy, eggs), people following vegetarian or vegan diets may be at higher risk of deficiency

The additive impact of combining a sympathomimetic with a GLP-1 agent has not been prospectively studied in rigorous trials