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Last Updated: July 13, 2026 Introduction to CPT2 Deficiency Carnitine palmitoyltransferase 2 (CPT2 or CPT-II) is one of a family of carnitine acyltransferases in humans that catalyze the reversible transfer of acyl groups between coenzyme A (CoASH) and L-carnitine, converting fatty acyl-CoA esters into fatty acyl-carnitine esters