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The injection should be given in pregnancy only if indicated, and under healthcare supervision

Further Western blot analysis showed that RRM2 regulated the expression levels of MMP2, MMP9 and EMT-related proteins (N-Cadherin, Vimentin, Snail), suggesting that RRM2 may promote tumor cell invasion and metastasis by promoting matrix degradation and inducing epithelial mesenchymal transition

Well, ideally, we want senescent cells to successfully kill themselves (kinda dark, I know, but its what keeps your body healthy!)

1 However, depending on the form taken, these medications can cause a slew of unwanted effects ranging from nausea and vomiting to lean muscle loss

"Effect of Opuntia ficus indica on symptoms of the alcohol hangover." Archives of internal medicine 164.12 (2004)