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When iron stores are sufficient, most intracellular Fe 2+ is sequestered in ferritin in an inactive form, while a small fraction forms the labile iron pool (LIP)

For example, if a phase I metabolite cant be cleared out quickly enough with phase II conjugation, then it can cause oxidative stress

The non-vitamin compounds (MIC) that are injected into the body stimulate the liver into optimizing the process of metabolism and providing the needed metabolic environment for fatty acid (fat) mobilization and utilization