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Other established ED treatments include: Vacuum erection devices Intracavernosal injections (alprostadil) Intraurethral alprostadil Testosterone replacement (for confirmed hypogonadism) Psychosexual therapy Penile prosthesis surgery (for refractory cases) All of these options have defined roles in ED management and are supported by clinical evidence

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No significant differences in hematological or serum biochemical parameters were observed between any treatment group and the control group (Additional file 2: Tables S8S9)

An intervention that suppresses inflammation at the wrong moment can impair the debridement and signaling that healing depends on