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As the body adjusts to the medication, some individuals may experience significant hair loss due to changes in the hair growth cycle

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GLP-1 is a gut hormone released after eating that signals the brain to reduce appetite, slows gastric emptying (so you feel fuller longer), stimulates insulin release from the pancreas, and suppresses glucagon (which would otherwise raise blood sugar)

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Efficacy results for the trial product estimand were broadly consistent with the treatment policy estimand