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Surgical interventions typically produce greater and more durable weight loss than pharmacotherapy alone and may be more appropriate than escalating to combination drug regimens with uncertain safety profiles

This aligns with our case

Furthermore, individual variability in ferroptosis sensitivity and redox metabolism poses additional barriers to standardized treatment

Most patients start during the dose escalation phase of tirzepatide (weeks 412) when oxidative stress from rapid fat loss is highest

EGCG is mainly absorbed in the intestine, where the gut microbiota has a fundamental role in its metabolism prior to absorption