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Once-weekly semaglutide in adults with overweight or obesity | New England Journal of Medicine, March 18, 2021

PMC 8717485

However, it is not approved for weight loss or heart protection like injectable semaglutide

[1] [2] This medication works by mimicking the action of the naturally occurring hormone GLP-1, which stimulates insulin secretion in a glucose-dependent manner, suppresses glucagon release, slows gastric emptying, and reduces appetite through central nervous system pathways

Each mechanism operates on a slightly different timeline, and together they create the layered response pattern that defines the semaglutide experience