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Neurotransmitter-induced inhibition of exocytosis in insulin-secreting beta cells by activation of calcineurin

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Extended validation DNG (PF-06882961) improves glucose tolerance and plasma insulin levels in genOhGLP-1R mouse model 13 genOhGLP-1R or WT mice were injected with DNG or vehicle and 15 minutes later administered 40% dextrose at 2g/kg