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10.1016/j.cmet.2011.08.016 Cell Metab
Semaglutide mimics glucagon-like peptide-1 (GLP-1), a gut hormone that slows gastric emptying, amplifies glucose-dependent insulin release, and acts on hypothalamic appetite centers to reduce hunger and food-seeking
The evidence base, such as it is, differs meaningfully across clinical targets, and it is worth examining each major application area on its own terms
A cAMP and Ca2+ coincidence detector in support of Ca2+ induced Ca2+ release in mouse pancreatic beta cells
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