In Study 5, the proportions of patients who discontinued study drug were 5.8% and 11.6% for WEGOVY and placebo, respectively
The primary degradation pathways include: Hydrolysis
For individuals prescribed Mounjaro for type 2 diabetes or weight management, regular monitoring should include HbA1c, fasting glucose, lipid profiles, renal function, and blood pressure, in line with NICE guidance (NG28 for type 2 diabetes, CG189 for obesity)
Important Limitations of Use : [1] Not recommended as first-line therapy for patients inadequately controlled on diet and exercise
Some patients may experience mild dehydration secondary to the gastrointestinal side effects commonly associated with Rybelsus, particularly nausea, vomiting, and diarrhoea