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Lipogenesis Inhibition: In adipose tissue, NNMT inhibition reduces lipid accumulation by up to 70% (in vitro), shifting the cell's priority from fat storage to energy expenditure

Interestingly, the paclitaxel-induced allodynia could be reduced by administering PEA through multiple routes, e.g., intrathecal, intraplantar and directly into the brain via intracerebroventricular injection, evidence that PEA can act on both the peripheral and central nervous system to achieve therapeutic efficacy

Alcohol is the most obvious culprit