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Within the study of hormesis in nutrition, it is important to make a distinction between the effects of individual food components and the broader phenomenon of dietary hormesis

Although an inflammatory phenotype was not detected in the brain, systemic immune dysregulation was suggested by significant decreases of IFN, TNF, IL-1, and IL10 (Zakirova et al., 2017)

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Excess vitamin B12 is linked to increased cancer growth in certain types of cancer.[ref] Methotrexate, a chemotherapy drug, works by inhibiting the production of methyl folate, thus limiting methionine and DNA synthesis for cell growth