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10.1016/j.jddst.2020.102310 17 BarazzuolL.CoppesR

Since ionizing radiation relies on ROS generation to induce DNA damage and promote apoptosis in cancer cells, the systemic or indiscriminate use of antioxidants could counteract this therapeutic mechanism

In fact, this study suggests that 5% of the cellular proteins are susceptible to glutathionylation, while in previous proteomics experiments we never identified more than 40 proteins in the whole proteome 16 and less than 50 are listed as glutathionylated in the NCBI or UniProt protein databases ( The big advantage of the redox array over more conventional mass spectrometry methods is the much greater sensitivity of this technique

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The rapid development of biomedical technologies introduces additional concerns