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It remains plausible that the reductions in MACE observed with oral semaglutide in the SOUL trialand as projected in our population-level modellingare at least partly attributable to direct GLP-1 receptor signalling, given the receptors expression in cardiovascular tissues and its downstream effects [11]

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Meta-analysis of the efficacy and safety of finerenone in diabetic kidney disease

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doi: 10.1111/ddg.14652 4 PicardoMDell'AnnaMLEzzedineKHamzaviIHarrisJEParsadDet al

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