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Ultimately, DeepRetro occupies a distinct niche: it harnesses the generative creativity of LLMs to bypass template limitations while enforcing the rigorous, tree-based logic of traditional CASP tools, offering a balanced trade-off between novelty, reliability, and computational accessibility

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The reported adverse events when implementing GLP1-RAs in this patient population were of gastrointestinal nature, mild and transient

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Subsequently, liraglutide (Saxenda) was approved in 2014 for the treatment of obesity up to a maximum dose of 3.0 mg subcutaneously once daily in people with a BMI 30 kg/m 2 , or 27 kg/m 2 and obesity-related co-morbidity [9, 17]