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tb may be of significant importance in conditions such as T2DM and HIV, as it may provide more potent defenses against immune dysregulation and excess inflammation, which, if uncontrolled, can precipitate severe outcomes such as organ failure and systemic infection

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The model was first fitted to the training concentrations (37.5 and 25 M doxorubicin), and then used to simulate the test concentrations (50, 12.5 and 10 M doxorubicin) as a means of blind validation, showing good accordance between the experimental and in silico outputs for all concentrations of doxorubicin

Clin Gastroenterol Hepatol 2015

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