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doi: 10.1002/mnfr.201700916

A portion of the iron in the cytoplasm is transported to the mitochondria for the synthesis of heme and iron-sulfur clusters (ISCs) [72]

These inhibitors can be broadly categorized based on their mechanisms of action, including iron chelators that limit the availability of redox-active iron, lipid peroxidation inhibitors that suppress oxidative stress, and activators of endogenous antioxidant pathways such as nuclear factor erythroid 2related factor 2 (NRF2) and GPX4 stabilization [10]

1 Hydroquinone was available previously in over-the-counter products and is currently available in prescription formulations with common concentration ranges of 0.4 to 5%

Quantitative analysis of estradiol and six other steroid hormones in human saliva using a high throughput liquid chromatographytandem mass spectrometry assay