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Clinical trials have determined that tirzepatide is associated with certain rare but serious adverse events in some patients, including developing pancreatitis, gallbladder problems, diabetic retinopathy, serious allergic reactions, or acute kidney injury

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Furthermore, as discussed in our previous review (Reference Ashoori and Saedisomeolia12) , riboflavin has also shown to have a protective effect against reperfusion oxidative injury (the tissue damage occurs after a period of ischaemia as a result of blood reperfusion) of different organs in experimental models, a finding which has been supported by the recent findings (Reference Adakul, Ertas and evikelli59Reference Li, Lu and Zhao62)

Intervention The intervention consisted of oral tap water with a low mineral content (Cristaline

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