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While the exact mechanism linking semaglutide to NAION is not fully understood, Kopelman told MNT , there are a few theories. He explained that semaglutide may influence vascular health and blood flow, potentially contributing to ischemic events in predisposed individuals. An ischemic event is when an organ or tissue does not receive adequate blood, and therefore oxygen

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Weeks 1 through 4: 2.5 mg per week

In a 12-week trial involving individuals with a BMI of 2743 kg/m, the highest-dose group achieved an 11.3% average weight reduction, a top-tier result for early-stage trials