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Furthermore, TH increases mitochondrial biogenesis and mitophagy, thereby maintaining mitochondrial quality for FAO

Individual variation matters Clinical trial averages mask enormous individual variation

Chloramphenicol and other drugs having bone marrow suppressant properties may cause a lack of therapeutic response to vitamin B12

These risks may be amplified in older patients due to underlying immune dysregulation associated with inflammaging. Implementing rigorous safety protocols, adapted from oncology, such as careful dose escalation and monitoring for autoantibodies, will be essential to ensure patient safety 118,119

In a similarly conducted experiment on Wistar rats, which additionally involved mild stress and utilized smaller doses of Epitalon, the quantity of IL-2-positive cells was examined