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1-4 PIONEER 2: In an open-label trial with a primary endpoint of mean change in A1C from baseline to Week 26, 822 adult patients with type 2 diabetes receiving metformin were randomized to semaglutide tablets 14 mg (n=412) or Jardiance 25 mg (n=410), both once daily

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The higher starting amount means a single vial can last through more of your dose escalation period, reducing the number of reconstitutions and minimizing the chance of concentration errors between vials