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Clayton PE, Banerjee I, Murray PG, Renehan AG: Growth hormone, the insulin- like growth factor axis, insulin and cancer risk
Clinical studies on GLP-1 compounds show dose-dependent effects, meaning lower doses produce measurable appetite suppression and metabolic benefitstypically 8-12% weight loss over 6-12 months at microdose levels
Whilst the market is currently led by Novo Nordisks semaglutide (Ozempic/Wegovy) and Eli Lillys tirzepatide (Mounjaro/Zepbound), stronger competition is expected as new entrants including Boehringer Ingelheim, Amgen, Pfizer and Roche offer novel mechanisms (dual agonists, triple agonists and amylins), formulations (oral vs injectable) and dosing regimens (daily vs weekly vs monthly)
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