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Consequently, the modern healthcare system cannot fully eliminate infection risk, particularly in post-surgical settings (Oliva et al., 2021

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To further prove the influence of intracellular GSH level on the cytotoxicity of NSBSO, we pre-treated 4T1 and B16 cells with GSH synthesis inhibitor to reduce the intracellular GSH level, and the results showed that the pretreatment of the inhibitors gradually reduced the intracellular GSH to a very low level after 24 h treatment (Additional file 1: Fig

A randomised controlled trial published in Clinical Infectious Diseases demonstrated that Thymosin Alpha-1 treatment in severe COVID-19 patients reduced 28-day mortality by 30% compared to standard care alone.17 While this was acute disease, not long COVID, it confirms the biological plausibility of the immune mechanism

[37] that high glucose induces PSC activation by OxS