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The exploration of these small molecules targeting ferroptosis provides valuable insights into the potential treatment of CKD

After extensive testing of various fragments, they identified a 15-amino acid sequence that exhibited the most potent protective and healing properties

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To this end, we evaluated multiple cellular parameters including loss of cell viability, caspase 3 activation, GSH-conjugate formation, GSH homeostasis, and cellular stress response pathway activation in mock- and GSTP1 -transfected HepG2 cells

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