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In their HDM mouse model, ginsenoside Rh1 treatment, notably at 50 mg/kg, caused a reduction inf frequency of sneezing and nose rubbing (Figure 10C), which coincided with substantial reduction of nasal tissue thickening, submucosal eosinophils, and IL-4+CD4+ cells, and enhancement of IFN- CD4+ cells [219]

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The accumulation of the results of these ongoing cardiovascular outcome trials should be able to answer questions about cardiovascular benefits of GLP-1 RAs that were strongly suggested by previous preclinical and clinical studies and their possibility to lower the excessive cardiovascular burden in patients with T2D