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Thiazolidinediones (TZDs) such as pioglitazone can also interact poorly with semaglutide, causing fluid retention or worsening heart failure symptoms in susceptible individuals

The FDA doesnt review compounded drugs for safety, effectiveness, or quality, though they are permitted to be prescribed under federal law at the prescribers discretion

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While there are pharmaceutical treatments for the excessive sleepiness associated with [obstructive sleep apnea], tirzepatide has the potential to be the first pharmaceutical treatment for the underlying disease, said Jeff Emmick, senior VP of product development at Eli Lilly