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Although most proteins required for mitochondrial function are encoded by nuclear DNA and synthesised by cytoplasmic ribosomes for targeted transport [30], regular respiratory chain activity requires structurally intact and functionally normal mitochondrial genes [31]

Hum Reprod 1996;11:387-391

Cerenius L, Kawabata SI, Lee BL, Nonaka M, Sderhll K (2010) Proteolytic cascades and their involvement in invertebrate immunity

The FDAs Pharmacy Compounding Advisory Committee voted in favor of expanding access to BPC-157, a popular peptide often marketed as a way to treat injuries, inflammation and potentially ulcerative colitis

Next, we measured the cristae width of hundreds of mitochondria and determined that rapamycin-treated CAR T cell products had significantly looser mitochondrial cristae, which is consistent with their less-activated metabolic state (Fig