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Specifically, the Patient Health Questionnaire (PHQ-9) score for depression dropped significantly from 13.03 to 9.84, and the Fibromyalgia Impact Questionnaire (FIQ) score dropped from 49.55 to 43.03

B12 and related B vitamins are worth special attention because many compounded GLP-1 formulations include B12 with semaglutide or B12 with tirzepatide precisely because reduced food intake lowers B vitamin status

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