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Why B12 Is Tier 2, Not Tier 1 The question I sometimes get is: if vitamin B12 deficiency is so common in post-weight-loss patients, why not just start everyone on it

Rhonda Patrick adds: "NAD+ precursors like NMN increase levels, aiding DNA repair and energykey for anti-aging."[34] She suggests stacking with NNMT inhibitors for sustained effects

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[21] Within cells, cyanocobalamin is converted to methylcobalamin and 5- deoxyadenosylcobalamin, coenzymes that participate respectively in homocysteine remethylation to methionine and in the isomerization of methylmalonyl-CoA to succinyl CoA, reactions essential for DNA synthesis, erythropoiesis, and myelin maintenance

For the foundational coverage of each compound individually, see What Is AOD-9604