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At the treatment day, mice received a single intraperitoneal injection of test items (200 g kg 1 , 50 nmol kg 1 ) formulated at 20 g mL 1 in PBS 1 or vehicle

however, it increases meal frequency by 162% or more, but with no effect on body weight [38]

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div-1 mutants exhibit loss of asymmetry during early embryonic cleavages and result in the lacking of the endodermal and mesodermal cell fates (Encalada et al., 2000)