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These EF-hand proteins are found both intracellularly and extracellularly

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10.1016/j.theriogenology.2014.10.002 51

36,286,332 In addition to participating in inflammatory responses, microglia and astrocytes also play key roles in maintaining brain homoeostasis by regulating synaptic morphology and plasticity

For example, consumption of GRP at a dose of 150 mol/kg body weight for 6 weeks increased the richness and diversity of bacterial species in C57BL/6 mice consuming a high-fat diet (HFD) ( TABLE 2 The effect of glucoraphanin and sulforaphane on the gut microbiota