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Briefly, PI (30 M) and digitonin (600 M) were added to each well and the fluorescence intensity was measured using a multimode microplate reader (Infinite F200

Starting GLP-1 medications with a gradual dose increase is key to helping your body adjust smoothly and lowering the chances of side effects like nausea, vomiting, or diarrhea

10.1186/s13041-020-00654-w 267

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When artemisinin consumes heme 25,26 (or iron 27 ) and produces free radicals or heme-artemisinin adducts to inhibit heme crystallization 28 , even accelerating the breakdown of hemozoin 5 , it simultaneously inevitably interferes the normal formation and degradation of hemozoin, uses up iron by forming iron-artemisinin within the parasites, interferes or interrupts the transport and utilization of iron, thereby finally leading to death of the malaria parasites