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4 Development of Arrhythmias Mechanisms by which arrhythmias can develop (Jaeger 2010): Enhanced or suppressed automaticity

In the case of drugs that are weak acids, acidic gastric contents reduce their degree of ionization, and this phenomenon may increase their absorption by diffusion

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The H-bond network is only observed for OCTN2 in the occluded conformation and is absent in the inward-facing conformation, supporting that the network helps to stabilise a kinked conformation of TM11 that packs against TM2

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